I went with three friends, all of us women in our mid 30s to early 40s, and had a fabulous time on the three day, two night kayak trip. We had all been on kayaking day trips before, but never on a multi-day kayaking trip. Also, though we are healthy and enjoy outdoor activities, we are not really athletic, and so were a little worried about the intensity of the activity, but we found it to be just right for us.
Our guide, Kevin, was top notch! We felt safe the entire time. We learned so much from him about the Everglades ecosystems and wildlife. He gave us pointers on kayaking more efficiently, and was continuously positive and cheerful from the morning coffee through the evening campfires. He was a great cook, and we enjoyed all three meals and snacks throughout the day. There were two vegetarians and both had plenty to eat.
We saw lots of wildlife including dolphins, rays, turtles, fish, osprey, a bald eagle, cormorants, etc. We camped on Picnic Key, and saw beautiful sunsets from the beach. A highlight of the three days was the mangrove tunnel which we paddled through, and swimming off the beaches.
The one downside that we encountered was the no-see-ums (small biting insects) that were only active in the morning before the breeze started. Once we were on (or in!) the water, or in the evenings when there was breeze, we had no trouble with the insects.
I highly recommend this to anyone of reasonable fitness who wants to get off the beaten path, and enjoys a little bit of adventure.